Quackery in Medicine: Low-Carb Diets

mvenus929's picture

Many people have heard of the Atkins diet in one way or another. Several of my family and friends went on this diet for a time, but found it hard to stick with the low-carbohydrate restrictions. After all, pasta and pizza are wonderful foods. The Atkins diet explains that people can lose weight by reducing their carbohydrate intake to 20 grams a day or less initially, then slowly raising them to levels to encourage ketosis. Carbohydrates include things like sugar, fruit, and grains.

Before we get into the possible ramifications of such a diet, let us examine the possible deficiencies that can result from such a diet. The B-complex vitamins are essential for life, especially for pregnant women. Folate, for instance, is necessary for neural tube development, and a deficiency can cause severe birth defects. In general, though, the B-complex vitamins are used for metabolism. They help break down foods and push them through the citric acid cycle, which produces a great amount of energy with each turn. Without these vitamins, you will feel more lethargic, which is why many 'energy' supplements contain large amounts of B-vitamins. B-vitamins are primarily found in whole grains, so cutting them from your diet means you need to take a supplement. Of course, this probably isn't covered when discussing the benefits of a low-carb diet.

Ketosis, some say, is "a normal physiological state caused by very normal and healthy body functions" by which the body breaks down fats and proteins and produces ketones as a result. In diabetics, ketosis is more commonly referred to as ketoacidosis. This occurs when the sugars of the blood cannot get into the cells (due to insulin resistance), and so the cells break down themselves for fuel. The resulting ketones lower the pH of the blood, causing it to become more acidic. This can lead to coma and death if not treated immediately.

Those who encourage ketosis in normal (non-diabetic) people claim that because the blood sugar levels remain consistent, ketoacidosis does not result. In fact, they claim, ketones are the "preferred fuel for the heart, outer part of the kidneys, and most areas of the brain."

First and foremost, that sentence is a lie. The brain requires glucose, which the simplest 6-carbon sugar, for fuel. Furthermore, glucose is the precursor to many neurotransmitters, such as acetylcholine and glutamate. When there is not glucose in the blood, the brain can use some ketones for energy, but not as efficiently, and it takes about two days of 'starvation' for adequate ketone levels to be produced. More often, when glucose is not available, loss of consciousness results, as is the case with hypoglycemia.

Of course, proponents of the Atkins diet will then say that your body can produce glucose, which it can. It breaks down fat and protein in an attempt to form glucose. Thus, by eating large amounts of fat and protein, you can keep your muscle mass up so you aren't breaking down your own body tissues. So, if you aren't eating enough protein to sustain your muscles, you could end up dying from a low-carb diet. After all, your heart is just as much of a muscle as your biceps. The heart also needs certain proteins to be at its optimum point. If you're using protein for energy, it takes away from being able to go towards what it was intended for: cellular regeneration.

Ketones are organic acids. Whether they lower your blood pH or not is mostly irrelevant (studies show they tend not to make non-diabetics have acidosis); they have to be excreted as waste one way or another. Most often, they are excreted through the urine (making your kidneys not so happy), as well as through your breath and sweat. Thus, people in ketosis tend to have a really bad body odor, which some describe as 'fruity' smelling. Since the absorption of glucose in a healthy person is near 100% and ketosis isn't nearly as efficient, someone on the Atkins, or similar, diet will excrete a whole lot of waste products, perhaps in some not-so-pleasant ways.

Bottom line: Your body needs energy to survive. The easiest source of energy is carbohydrates, because fats and proteins, while able to produce just as much or more energy, have other functions in the body. If you want to lose weight, keep a balanced diet and exercise program going for the long term. You won't lose a lot real fast, but you'll be healthy and will be more likely to keep the weight off long-term.

bridge's picture
Volunteer for the Progressive U Alumni Association

I already feel I've learned so much from your "Quakery in Medicine" series.

I've felt that some diets cannot possibly be good for the body. Especially those that tout the easy way out, by eating nothing but (insert brand aname or food product here). Eliminating carbs never seemed right. Carbs are needed for energy, correct? So they are better for more active people. But if some couch potato wants to eat a lot of carbs, there may be a problem. Cutting back a little can't hurt.

However, if we believe some of these "experts", you'd think we can't eat anything starchy, anything with carbs, anything with sugar, or any vegetables, because they might make you feel bloated.

I'd rather just eat normal, not overindulge (at least not all the time) and try to be a little active. Seems like the safer way in the long run.

afungus amongus's picture

Blessed with a lightning fast metabolism and chances to work out, I'm on the "eat what you want" diet, albeit with balance and protein considerations in mind. I knew Atkins meant eating steaks, but I didn't realize it made you cut back on carbs. Yuck. I'm with you guys, move more rather than eat less.

kinkatia's picture
Member of the Progressive U Alumni Association

I knew the Atkins diet wasn't very healthy, but I didn't know all of this. Yikes. People really need to realize that the body is a complex system, and needs to be properly taken care of. Quick fixes won't hold out in the long run.

This was a very informative blog entry. I'll keep it in mind to pass on to the next person who mentions wanting to go on this sort of diet.

And that's comin' at ya' from yer local redneck hippie.
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turtlesuds's picture
Volunteer for the Progressive U Alumni Association

I tried the Atkins diet for a time and did lose weight, one thing i did not know would result was that my hair became very brittle and dry and started to come out in handfuls in the shower. I didnt know it was because of my diet at first until i went off of it, my hair went back to normal, and then i went back on the diet and it happened again.

I get very irritated when people push bad advice about losing weight. Dr. Atkins died at a young age btw, what i had heard was that he slipped and fell and apparently his heart was so weak it killed him. i know you know, but for the benefit of readers, the fat around our organs exists to keep them in place and provides a certain level of protection. I havent verified the actual cause of his death yet, that was just what i heard.

Recently some nurses i work with are pushing a weight loss program that uses HCG (the hormone present in urine that causes a pregnancy test to come up positive) and extremely low calorie diet (around 800 calories a day). personally, i am highly skeptical of anything that relies on hormones for anything. my instincts tell me that when we mess with hormones we increase chances of cancer. also, the fad of using human growth hormone as "anti-aging" agents bothers me too, and is extremely popular here in southern ca.

I was wondering if you had any thoughts or information about these?

"O, I'm sorry you took that, -I meant that for the Devil, and you have stepped in and taken the blow. Don't get between me and the Devil, brother, and the you won't get hurt." --Billy Hibbard

mvenus929's picture
Managing Director of Progressive U

I believe Atkins died from the trauma to his head (maybe an aneurysm?), not his heart. But, this is from forums I've read, not an actual article.

Anything that demands you eat less than about 1200 calories a day is absolutely ludicrous. This is the amount of calories you need every day to do simple things like breath, shift in your seat, keep your heart beating and your brain cells firing. Yes, you will lose weight if you eat less than that, but you'll be doing it at the expense of things that are rather important, such as that fat around your organs. It's much safer to raise your basal metabolism (via exercise) than it is to just cut your calorie intake.

I agree that messing with hormones isn't good. After all, body builders who use testosterone (or other derivatives) end up aggressive, and eventually impotent and unable to function. Our hormones are in a delicate balance in the body, and disrupting that balance can throw things off that we didn't intend to throw off in the first place. There's a reason there's so many different varieties of hormone contraceptives.

~C
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turtlesuds's picture
Volunteer for the Progressive U Alumni Association

i think it does have its place, with contraception and replacement therapy for menopause but beyond that i think the risks outweigh the benefits...

maybe your next blog in this series can address this more comprehensively? i would be very interested to know your pov as a prospective medical student...where should we stop?

"O, I'm sorry you took that, -I meant that for the Devil, and you have stepped in and taken the blow. Don't get between me and the Devil, brother, and the you won't get hurt." --Billy Hibbard

mvenus929's picture
Managing Director of Progressive U

I shall look into that a little more for you :)

~C
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Volunteer for the Progressive U Alumni Association

As one who's had to deal with the effects of hormones on weight loss, I find that diet highly suspect, to say the least (I can't speak for the effectiveness or safety of that particular one, however, because I'm no doctor or even med student, I can only speak for my own experiences).

I was on Depo Provera birth control ("the shot") for about a year. Of course, like any other hormone-base birth control, Depo screwed with my hormones. A year after I stopped taking it, my hormones were still screwy and weren't cycling like they should, but were instead in a constant "high" state.

Combine that with high insulin resistance (which may have already been present, as I've always had low blood sugar), and I couldn't lose any weight, at all, no matter what I did, and by that time, I was averaging 1500-1800 or so calories a day (I didn't keep close track, so some days were more, some were less), and an hour or so of exercise, most days a week (and no, I'm not talking about, "oh, I'm only losing half a pound a week, I'm talking I did a year of this and never dropped below two pounds below my average weight, which is within the daily fluctuation range). Not only did it keep me from losing weight, but it also stopped my menstrual cycle.

(Note: you may have noticed by now that the symptoms sound like PCOS, which would have been a simple enough diagnosis had there actually been any cysts. Regardless, my hormones were still screwy.)

And this was "just" the androgens (testosterone, progesterone, estrogen). From the quick search I did on HCG, I see that it keeps progesterone levels elevated, so yeah, definitely stay away from that diet, in my opinion.



I am treated as evil by people who claim that they are being oppressed because they are not allowed to force me to practice what they do. ~D. Dale Gulledge

mvenus929's picture
Managing Director of Progressive U

A high insulin resistance would lead to a high blood sugar, not a low one. That's one of the causes/effects of diabetes. Basically, the blood sugar is too high, so your pancreas creates insulin to drop your blood sugar, except your cells don't respond to the insulin, so your blood sugar levels remain elevated, and thus begins a vicious cycle. A high insulin level would cause a low blood sugar, if your cells are responding properly.

~C
Check out the latest entry in the Between The Lines column!
Want the highest rated list to change? RATE those blogs, then!

Volunteer for the Progressive U Alumni Association

It seems I was a little confused about how, exactly, insulin works. Thank you for clarifying it. As I said before, I'm no doctor or even med student.

Why is it, then, that as one who has been diagnosed with high insulin resistance, I also had low blood sugar? (I do not, and did not, have diabetes, FYI.)



I am treated as evil by people who claim that they are being oppressed because they are not allowed to force me to practice what they do. ~D. Dale Gulledge

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